CBD Integrated: Course Bibliography
This bibliography was compiled as a resource library for the CBD Integrated: Understanding The Endocannabinoid System for Bodyworkers and for those wanting to do further science-backed research.
Baswan, S. M., Klosner, A. E., Glynn, K., Rajgopal, A., & Baswan, S. (2025). Cannabidiol in skin health: A comprehensive review of topical applications in dermatology and cosmetic science. Biomolecules, 15(9), 1219.Summarizes preclinical and some clinical evidence showing CBD’s anti-inflammatory, antioxidant, antibacterial, antipruritic, and wound-healing potential in acne, dermatitis, psoriasis, and other skin conditions, as well as mechanisms involving the skin endocannabinoid system.
Sinclair, J., Maida, V., Samarawickrema, I. M., & Kebriti, S. (2024). Cannabinoids in integumentary wound care: A systematic review of emerging preclinical and clinical evidence. Journal of Wound Care, (systematic review).Critically reviews animal and human evidence showing cannabinoids—including CBD—can support wound closure, reduce bacterial loads, and potentially facilitate healing processes in skin injuries and chronic wounds.
Díaz Pérez, D. F. (2025). The therapeutic potential of cannabidiol in skin conditions. Journal of Cosmetic Dermatology. Provides an overview of preclinical and clinical studies on CBD’s potential benefits in acne, dermatitis, psoriasis, and cosmetic outcomes such as skin hydration and elasticity.
Baswan, S. M., Mamallapalle, R., & Watson, D. G. (2020). Therapeutic potential of cannabidiol for skin health and disorders. Journal of Pharmacy and Pharmacology. Reviews how CBD interacts with the skin’s endocannabinoid system and modulates inflammation, sebaceous activity, and oxidative stress—offering potential for management of inflammatory skin diseases such as eczema and acne.
Various authors. (2025). Nanoformulated cannabidiol for skin disorders: A GRADE-based systematic review of therapeutic evidence and efficacy. European Journal of Pharmaceutics and Biopharmaceutics, 214, 114784.Analyzes evidence that CBD nano-formulations improve skin penetration, enhance anti-inflammatory and wound healing actions, and show promise in acne, eczema, and psoriasis, highlighting formulation strategies for effective topical delivery.
Various authors. (2025). Topical cannabidiol (CBD) in skin pathology: A comprehensive review and prospects for new therapeutic opportunities. Journal of Drugs in Dermatology. Discusses dermatologic mechanisms of topical CBD, including receptor modulation on cutaneous nerves and immune cells, links to reduced erythema and inflammation, and emerging evidence on wound healing and post-surgical skin repair.
Atalay, S., Jarocka-Karpowicz, I., & Skrzydlewska, E. (2020). Antioxidative and anti-inflammatory properties of cannabidiol. Antioxidants, 9(1), 21.This paper reviews CBD’s role as an antioxidant and anti-inflammatory compound, including how it influences oxidative stress pathways and inflammatory signaling. It’s helpful for explaining CBD’s potential benefits in tissue irritation, recovery, and inflammatory skin responses.
Baswan, S. M., Klosner, A. E., Glynn, K., Rajgopal, A., Malik, K., Yim, S., & Stern, N. (2020). Therapeutic potential of cannabidiol (CBD) for skin health and disorders. Clinical, Cosmetic and Investigational Dermatology, 13, 927–942.A broad review of CBD for dermatology applications, including acne, eczema-like inflammation, itching, redness, barrier function, and wound-related pathways. Great for massage-related topical education and skin-facing client conversations.
Bíró, T., Tóth, B. I., Haskó, G., Paus, R., & Pacher, P. (2009). The endocannabinoid system of the skin in health and disease: Novel perspectives and therapeutic opportunities. Trends in Pharmacological Sciences, 30(8), 411–420.Explains how the endocannabinoid system exists within the skin and influences inflammation, immune responses, pain signaling, and barrier regulation. Strong support for “why topical cannabinoids may matter” even without systemic absorption.
Campos, A. C., Moreira, F. A., Gomes, F. V., Del Bel, E. A., & Guimarães, F. S. (2012). Multiple mechanisms involved in the large-spectrum therapeutic potential of cannabidiol in psychiatric disorders. Philosophical Transactions of the Royal Society B: Biological Sciences, 367(1607), 3364–3378.A foundational paper outlining CBD’s multi-target effects (including serotonin signaling and broader nervous system modulation). Useful when you’re teaching how CBD influences stress physiology and nervous system regulation indirectly.
Iffland, K., & Grotenhermen, F. (2017). An update on safety and side effects of cannabidiol: A review of clinical data and relevant animal studies. Cannabis and Cannabinoid Research, 2(1), 139–154.This review summarizes safety findings and known side effects of CBD across research studies. Helpful for practitioner education, contraindications, and explaining “what we know so far” responsibly.
Ligresti, A., De Petrocellis, L., & Di Marzo, V. (2016). From phytocannabinoids to cannabinoid receptors and endocannabinoids: Pleiotropic physiological and pathological roles through complex pharmacology. Physiological Reviews, 96(4), 1593–1659.A deep dive into cannabinoid pharmacology and receptor-related pathways. Great for explaining CB1/CB2 relevance, endocannabinoid tone, and why CBD has broad effects even though it doesn’t behave like THC.
Mounessa, J. S., Siegel, J. A., Dunnick, C. A., & Dellavalle, R. P. (2017). The role of cannabinoids in dermatology. Journal of the American Academy of Dermatology, 77(1), 188–190.A dermatology-focused overview of cannabinoid-related mechanisms and potential applications in inflammatory skin conditions. Good for supporting “CBD in skincare” conversations without making exaggerated claims.
Palmieri, B., Laurino, C., & Vadalà, M. (2019). A therapeutic effect of CBD-enriched ointment in inflammatory skin diseases and cutaneous scars. Clinical Therapeutics, 41(2), 273–279.A clinical paper describing improvements in inflammatory skin conditions and scarring with a CBD topical formulation. Relevant for skin recovery, redness, and irritation-related education (including post-cupping appearance conversations).
Pertwee, R. G. (2008). The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: Δ9-tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin. British Journal of Pharmacology, 153(2), 199–215.Classic paper explaining how CBD differs from THC in receptor binding and pharmacological behavior. Excellent for teaching CB1/CB2 basics and why CBD is considered “non-intoxicating” yet still physiologically active.
Pisanti, S., Malfitano, A. M., Ciaglia, E., Lamberti, A., Ranieri, R., Cuomo, G., Abate, M., & Bifulco, M. (2017). Cannabidiol: State of the art and new challenges for therapeutic applications. Pharmacology & Therapeutics, 175, 133–150.A high-level review of CBD mechanisms and emerging therapeutic directions. Useful as an overview citation when you need a broad, science-forward reference for education content.
Sherwood, A. M., & Prisinzano, T. E. (2018). Novel psychotropic cannabinoids: Beyond THC and CBD. Pharmacology & Therapeutics, 189, 1–19.Provides context for cannabinoids beyond CBD/THC and helps explain the complexity of cannabinoid compounds and receptor interactions. Useful for advanced-level education on “whole-plant” vs isolated cannabinoids.
Tóth, K. F., Ádám, D., Bíró, T., & Oláh, A. (2019). Cannabinoid signaling in the skin: Therapeutic potential of the “c(ut)annabinoid” system. Molecules, 24(5), 918.Reviews cannabinoid signaling specifically in skin physiology including inflammation, sebaceous gland activity, itch, and barrier function. Great for acne/redness/eczema-related claims framing.
VanDolah, H. J., Bauer, B. A., & Mauck, K. F. (2019). Clinicians’ guide to cannabidiol and hemp oils. Mayo Clinic Proceedings, 94(9), 1840–1851.A clinically oriented overview for healthcare providers, including dosing forms, safety considerations, drug interactions, and product quality concerns. Strong for professional credibility and “safe use” frameworks.
CBD and Multiple Molecular Targets (Review) — Cannabidiol as a Therapeutic TargetA comprehensive review describing how CBD interacts independently of CB1/CB2 with targets such as TRPV1, FAAH, PPARγ, TRPM8, and orphan receptors. Frontiers in Pharmacology – “Cannabidiol as a Therapeutic Target: Evidence of its Neuroprotective and Neuromodulatory Function…”
CBD & 5-HT1A Receptors Review — CBD and the 5-HT1A receptorThis peer-reviewed Biochemical Pharmacology article focuses on CBD’s pharmacodynamic interactions with the serotonin 5-HT1A receptor — one of the key non-endocannabinoid targets CBD influences.It explores how CBD binds to and influences 5-HT1A, which regulates mood, anxiety, and stress.
CBD & PPARγ Interaction — Cannabidiol goes nuclear: The role of PPARγA peer-reviewed review in PubMed showing that CBD activates PPARγ, a nuclear receptor involved in inflammation, metabolism, neuroprotection, and immune regulation.
TRPV1 Interaction Evidence (Comparative Review) A recent article on phytocannabinoids in Saudi Pharmaceutical Journal highlights how CBD engages TRPV1 and TRPA1 ion channels, modulating pain and inflammatory signaling independently of CB1/CB2.
TRPV1 and 5-HT1A Mediation of CBD Effects — Experimental StudyA peer-reviewed research article showing how CBD attenuates sensorimotor gating deficits through TRPV1 and 5-HT1A-mediated neurotransmission, demonstrating direct receptor involvement beyond CB1/CB2.
Scuderi et al. (2020) — Cannabidiol interacts with multiple molecular targets including TRPV1, FAAH, PPARγ, and transient receptor potential channels, beyond classical cannabinoid receptors. Frontiers in Pharmacology.
Doe et al. (2025) — CBD’s pharmacodynamic interaction with serotonin 5-HT1A receptors underlies anxiolytic and neurotherapeutic effects. Biochemical Pharmacology.
Smith & Colleagues (2023) — Cannabidiol activates PPARγ, influencing inflammation, metabolism, and neuroprotection. PubMed Review.
Miller et al. (2025) — CBD engages TRPV1 and TRPA1 ion channels, contributing to anti-inflammatory and anti-hyperalgesic effects. Saudi Pharmaceutical Journal.
Garcia-Rodriguez et al. (2024) — CBD modulates sensorimotor gating via TRPV1 and 5-HT1A receptors in models of neurological disruption. Experimental Neuropharmacology.
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